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. 2009 Jul 20;106(30):12542–12547. doi: 10.1073/pnas.0901647106

Fig. 5.

Fig. 5.

Local production of E regulates uterine neovascularization during decidualization. Mice were subjected to artificial decidual stimulation in the presence or absence of letrozole. Uteri were collected at 72 h following the decidual stimulation and frozen tissue sections were subjected to immunohistochemical analysis using an antibody specific for PECAM-1. (A and C) PECAM-1 expression in uteri of mice without letrozole treatment. (B and D) PECAM-1 expression in uteri of mice treated with letrozole. M, mesometrial area.