Fig. 5.

Significant telomere loss in Ku86 null cells. (A) A total of 76 metaphases were scored for the percentage of SFEs, and the number of metaphases containing 0–10%, 10–20%, etc. SFEs is shown. Every metaphase had at least 20–30% SFEs, and most metaphases exhibited 70–80% SFE. (B) Ku86 null cells undergo telomere loss. The indicated cell lines were subjected to the indicated treatments and scored for SFEs. Total Chrs*, total chromosomes. The number is smaller than the theoretical total because some metaphases contained <46 distinguishable chromosomes, and only chromosomes that could be unambiguously scored were included.