TABLE 1.
Albumin–fluorescein isothiocyanate, 22na+, and [3h]mannitol fluxes across alveolar–capillary barrier did not change during the different conditions of the experimental protocol
| Group pH/PCO2 (mm Hg) |
FITC Flux (ml/h) |
22Na Flux (ml/h) |
[3H]Mannitol Flux (ml/h) |
|---|---|---|---|
| 7.40/40.8 | 0.020 ± 0.004 | 1.06 ± 0.11 | 0.55 ± 0.03 |
| 7.50/32.1 | 0.010 ± 0.006 | 1.84 ± 0.38 | 1.17 ± 0.18 |
| 7.60/25.2 | 0.020 ± 0.003 | 2.29 ± 0.40 | 1.36 ± 0.40 |
| 7.70/14.6 | 0.015 ± 0.007 | 2.10 ± 0.17 | 1.35 ± 0.17 |
| 7.40/29.6 | 0.026 ± 0.002 | 1.25 ± 0.31 | 0.89 ± 0.15 |
| 7.40/19.8 | 0.017 ± 0.005 | 1.26 ± 0.44 | 0.58 ± 0.28 |
| 7.40/13.2 | 0.020 ± 0.010 | 1.29 ± 0.4 | 0.61 ± 0.1 |
| 7.70/38.7 | 0.02 ± 0.008 | 1.07 ± 0.25 | 0.42 ± 0.08 |
Definition of abbreviation: FITC = fluorescein isothiocyanate.
Values represent mean ± SEM. PCO2 levels as described in RESULTS.