Figure 1.
Cu,Zn-SOD (superoxide dismutase) protein, Mn-SOD protein, and total SOD activity in serum of control subjects (n = 20), subjects with nonsevere asthma (n = 74), and subjects with severe asthma (n = 40). Subjects with asthma have decreased SOD activity compared with control subjects (analysis of variance [ANOVA], p = 0.001), and SOD activity levels of subjects with severe and nonsevere asthma are similarly reduced. There is no significant difference in Mn-SOD (ANOVA, p = 0.416) or Cu,Zn-SOD levels among nonsevere, severe asthma, or control groups (ANOVA, p = 0.165), although subjects with asthma as a group tend to have more Cu,Zn-SOD than do control subjects (t test, p = 0.057).