Sensitivity (A), specificity (B), and positive predictive value (C) for obstructive (solid lines) and restrictive (dashed lines) lung disease for BOS 0-p defined by both FEV1 (thin lines) and FEF25–75% (bold lines) criteria. The sensitivity for obstructive versus restrictive lung disease was not significantly different for BOS 0-p FEV1 (p = 0.24), but was significantly different for BOS 0-p FEF25–75% (p = 0.04). The specificity for obstructive versus restrictive lung disease was significantly different for BOS 0-p FEV1 (p = 0.05), but was not significantly different for BOS 0-p FEF25–75% (p = 0.31). The positive predictive values for obstructive versus restrictive lung disease was significantly different for BOS 0-p FEV1 (p = 0.01), but was not significantly different for BOS 0-p FEF25–75% (p = 0.44).