TABLE 1.
Clinical histories associated with autopsy specimens
| Case ID | Sex | Birth Weight (g) | Gest Age at Birth (wk) |
Postnatal Age at Death (d) |
Gest Age at Death (wk) |
Autopsy Diagnosis | FiO2 > 50% (d) | On IMV (d) |
|---|---|---|---|---|---|---|---|---|
| No lung disease | ||||||||
| Case 1 | F | 2,580 | 36 | 2 | 36 | Hypoxic-ischemic encephalopathy | 2 | 2 |
| Case 2 | F | 1,880 | 36 | 4 | 37 | Severe microcephaly | 2 | 4 |
| Case 3 | F | 2,035 | 40 | 5 | 41 | Pena-Shokeir phenotype | 0 | 1 |
| BPD | ||||||||
| Case 4 | M | 825 | 27 | 97 | 40 | BPD, periventricular leukomalacia | 96 | 97 |
| Case 5 | F | 910 | 26 | 60 | 35 | BPD, brain infarct | 23 | 32 |
| Case 6 | M | 520 | 25 | 65 | 34 | BPD, cytomegalovirus infection, hypertropic cardiomyopathy | 30 | 62 |
| Case 7 | M | 1,021 | 28 | 13 | 30 | BPD, intrauterine growth retardation, cytomegalovirus | 13 | 13 |
| Sepsis | ||||||||
| Case 8 | F | 620 | 25 | 18 | 27 | Necrotizing enterocolitis, pulmonary hemorrhage, BPD | 7 | 18 |
| Case 9 | M | 1,037 | 27 | 1 | 27 | Acute chorioamnionitis with funisitis | 1 | 1 |
| Case 10 | F | 1,210 | 28 | 32 | 33 | Fulminate necrotizing enterocolitis | 3 | 3 |
| Case 11 | M | 1,940 | 31 | 5 | 32 | E. coli sepsis | 5 | 4 |
Definition of abbreviations: BPD = bronchopulmonary dysplasia; Gest = gestational; IMV = intermittent mandatory ventilation.