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. 2005 Jun 3;172(4):470–479. doi: 10.1164/rccm.200411-1547OC

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Figure 6. — Changes in lung NOS activity in response to MV. (A) iNOS activity. There was no detectable iNOS activity in lungs of iNOS^−/− mice breathing spontaneously (controls) or exposed to HVT. In contrast, there was minimal iNOS activity in control WT mice, with a significant increase in response to HVT (n ⩾ 4 for each condition). *p < 0.05 versus control animals. (B) eNOS activity. At baseline (spontaneous breathing), lungs of both WT and iNOS^−/− mice displayed activity. HVT resulted in a mild decrease and a significant increase in that activity in WT and iNOS^−/− mice, respectively. *p < 0.05 versus control animals.

Figure 6. — Changes in lung NOS activity in response to MV. (A) iNOS activity. There was no detectable iNOS activity in lungs of iNOS^−/− mice breathing spontaneously (controls) or exposed to HVT. In contrast, there was minimal iNOS activity in control WT mice, with a significant increase in response to HVT (n ⩾ 4 for each condition). *p < 0.05 versus control animals. (B) eNOS activity. At baseline (spontaneous breathing), lungs of both WT and iNOS^−/− mice displayed activity. HVT resulted in a mild decrease and a significant increase in that activity in WT and iNOS^−/− mice, respectively. *p < 0.05 versus control animals.