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Analysis of the different mutants
| Virus | pfu/ml | Replication centres/ml | VP1 Productiona | Assemblya | Stability half lifeb(min) |
|---|---|---|---|---|---|
| SV40-WT | 1.2×109 (3) | 2.3×108 (9) | 100 | 100 (4) | 20.5 |
| SV40-P300A | 2.5×105 (2) | 7×106 (4) | 65 | 100 (2) | 5 |
| SV40-P300G | <102 (2) | 4.2×105 (4) | 63 | 67 (3) | 5 |
| SV40-Y299F | - | 2.8×107 (3) | 93 | 34 (1) | 14 |
| SV40-Y299T | - | 6.8×104 (3) | 60 | 22 (1) | 8.5 |
| SV40-Y299A | - | 4.5×102 (3) | 68 | 34 (1) | 6.5 |
| SV40-ΔC47 | <102 (2) | <102 | ND | 2 (1) | ND |
- calculated as % of WT
- at 37°C
