TABLE 2.
Genes differentially expressed in bronchioloalveolar carcinoma versus adenocarcinoma-mixed subtype
| Probe | Gene Description | GenBank | Gene Category | p Value | ||||
|---|---|---|---|---|---|---|---|---|
| Genes Highly Expressed in AC-Mixed Type Compared with BAC Tumors | ||||||||
| 4095_at | PI-3-kinase–related SMG-1-like (KIAA0220) | AL049250 | Unknown function | 0.0003181 | ||||
| 40004_at | Sine oculis homeobox homolog 1 (SIX1) | X91868 | Transcription factor | 0.0007989 | ||||
| 35369_at | Deltex 4 homolog (DTX4) | AB023154 | Unknown function | 0.0018299 | ||||
| 40617_at | THUMP domain containing 1 | AC004381 | Unknown function | 0.0022976 | ||||
| 35007_at | TWIST neighbor | AC004940 | Unknown function | 0.0025262 | ||||
| 32107_at | cDNA c21orf25 | AL050173 | Unknown function | 0.0029529 | ||||
| 40717_at | Cathepsin L2 | AB001928 | Cysteine proteinase | 0.0073467 | ||||
| Genes Highly Expressed in BAC Compared with AC-Mixed Type Tumors | ||||||||
| 34840_at | cDNA FLJ22642 | AI700633 | Unknown function | 9.51E-05 | ||||
| 32168_s_at | Down syndrome critical region gene 1 | U85267 | Calcineurin-mediated signaling regulation | 0.0005758 | ||||
| 41267_at | mRNA for KIAA1049 | AB028972 | Unknown function | 0.0015624 | ||||
| 280_g_at | NR4A1 | L13740 | Steroid-thyroid hormone-retinoid receptor superfamily | 0.0018289 | ||||
| 31525_s_at | Hemoglobin, α pseudogene 1 | J00153 | Unknown function | 0.0020264 | ||||
| 206_at | Cathepsin E (CTSE) | M84424 | Aspartic proteinase | 0.0024424 | ||||
| 40659_at | NR4A3 | U12767 | Steroid-thyroid hormone-retinoid receptor superfamily | 0.0032117 | ||||
| 38037_at | Diphtheria toxin receptor (DTR) | M60278 | EGF-like growth factor | 0.0039134 | ||||
| 34246_at | cDNA C6orf145 | AA418437 | Unknown function | 0.0039684 | ||||
| 1814_at | TGFBRII | D50683 | Serine/threonine kinase receptor | 0.0043177 | ||||
| 37028_at | Protein phosphatase 1, regulatory subunit 15A | U83981 | Serine threonine kinase/protein phosphatase | 0.0044977 | ||||
| 271_s_at | CTSE | J05036 | Aspartic proteinase | 0.0047981 | ||||
| 35008_at | Period homolog 2 (PER2) | AB002345 | Ciracadian regulator | 0.004922 | ||||
| 33699_at | Pepsinogen C (PGC) | M18667 | Aspartic proteinase | 0.0049418 | ||||
| 1815_g_at | TGFBRII | D50683 | Serine/threonine kinase receptor | 0.0050199 | ||||
| 34721_at | FKBP5 | U42031 | Peptidylprolyl isomerase | 0.0052014 | ||||
| 38717_at | DKFZP586A0522 | AL050159 | Methyltransferase | 0.0061461 | ||||
| 36134_at | Olfactomedin 1 (OLFM1) | U79299 | Neuronal glycoprotein | 0.0062414 | ||||
| 1583_at | TNFRSF1B | M32315 | TNF-receptor superfamily | 0.0071696 | ||||
| 32563_at | ATPase, β3 | U51478 | Na+/K+ and H+/K+ ATPase | 0.0076784 | ||||
| 32893_s_at | γ-glutamyltransferase 1 (GGT1) | M30474 | Transferase protein | 0.007909 | ||||
| 1519_at | ETS2 | J04102 | Transcription factor | 0.0095507 | ||||
| 41268_g_at | mRNA for KIAA1049 protein | AB028972 | Unknown function | 0.0099509 | ||||
Definition of abbreviations: AC = adenocarcinoma; BAC = bronchioloalveolar carcinoma; EGF = epidermal growth factor; TNF = tumor necrosis factor.