Fig. 4.
Reversal of the direction of tangential migration of a stellate/basket cell at the top of the ML. (A) Time-lapse series of images showing the reversal of tangential migration of a stellate/basket cell at the top of the ML of P9 mouse cerebellum. Elapsed time after in vitro (in hours) is indicated on the top-right of each photograph. Asterisks mark the soma. Scale bar; 21 µm. (B1-B3) Pseudocolor images represent images of the stellate/basket cell taken every half hour shown in A. Nine images, eight images, and seven images of the cell are superimposed in B1, B2, and B3, respectively. The numbers represent elapsed time after in vitro (in hours). Scale bar; 22 µm. (C1 and C2) The total distance traversed by the cell (C1) shown in A and the direction and distance traveled by the cell during each half hour of the testing period (C2) were plotted as a function of elapsed time after in vitro. In C2, positive values represent tangential cell movement towards the rostral direction, while negative values represent tangential cell movement towards the caudal direction.