Table II.
Number of Rearrangements | B cell Source | Invading Gene | Recipient Gene |
---|---|---|---|
1 | Fetal liver pre/pro CD19+IgM- | VH4-39 | VH4-4 |
2 | Fetal marrow immature CD19+IgM+ | VH4-59 | VH4-b |
28 | X-HIgM mature CD19+ | VH4-59 | VH4-b |
1 | X-HIgM mature CD19+ | VH4-59 | VH4-34 |
24 | AICDA deficient CD19+ | VH4-59 | VH4-b |
A total of 53 fetal liver, 72 fetal bone marrow and 327 X-HIgM rearrangements were analyzed for pseudohybrid joins. An additional 284 AICDA deficient VH4 B cell rearrangements were analyzed specifically for VH4-59/4b pseudohybrid joins.