Figure 5.

Lissoclinidine B (5) activates p53 transcription. U2OS-pG13 cells were incubated with 1 µg/ml adriamycin, or 1–10 µM 5 for 22 h. After the incubation, luciferase activity was assessed. Data represents average and standard deviation of three independent experiments. RLU: relative light unit. Adr: adriamycin.