Table 2.

Partial correlation^§ of number of children and Alzheimer’s disease neuropathology-df=38 for women and 27 for men(r; p-value).

AD Neuropathology	Women	Men
Neuritic Plaques (NPs)
Hippocampus	.24 (.14)	−.08 (.66)
Entorhinal Cortex	.29 (.06)	−.10 (.59)
Amygdala	.47 (.002)	.11 (.59)
Cerebral Cortex	.22 (.18)	−.14 (.48)
Total NPs	.36 (.02)	−.10 (.59)
Neurofibrillary Tangles (NFTs)
Hippocampus	.18 (.26)	.07 (.73)
Entorhinal Cortex	.15 (.37)	.24 (.22)
Amygdala	.22 (.16)	.03 (.87)
Cerebral Cortex	.22 (.18)	.09 (.64)
Total NFTs	.26 (.10)	.12 (.52)
General neuropathology score$	.37 (.02)	.02 (.93)

^§Controlling for age at death and CDR

^$first principal component of a factor analysis including NPs and NFTs in the hippocampus, entorhinal cortex, amygdala, and cerebral cortex.