Table 3.
Summary statistics for the two best individual predictors for STAT5 binding sites
Predictor(s) | TP | TN | FP | FN | Sensitivitya | Specificityb | PPVc | NPVd | Accuracye |
---|---|---|---|---|---|---|---|---|---|
≥1 consensus site in rat | 15 | 46 | 15 | 3 | 0.83 | 0.75 | 0.50 | 0.94 | 0.77 |
Matrix 459 | 17 | 45 | 16 | 1 | 0.94 | 0.74 | 0.52 | 0.98 | 0.78 |
Matrix 459 + consensus site | 15 | 50 | 11 | 3 | 0.83 | 0.82 | 0.58 | 0.94 | 0.82 |
True positives (TP), true negatives (TN), false positives (FP), false negatives (FN), sensitivity, specificity, PPV, NPV, and accuracy (see definitions in Table footnotes) for the two best individual predictors and the combination of the two are listed.
Sensitivity = TP/(FN + TP);
Specificity = TN/(FP + TN);
PPV = TP/(TP + FP);
NPV = TN/(FN + TN);
Accuracy = (TP + TN)/(TP + TN + FP + FN).