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. Author manuscript; available in PMC: 2010 May 1.
Published in final edited form as: Dev Cell. 2009 May;16(5):756–763. doi: 10.1016/j.devcel.2009.03.003

Figure 3. Constitutive activation of Wg signaling blocks differentiation of hemocyte precursors.

Figure 3

Genotypes are shown on top of corresponding panels. In wild type 3rd instar LG the cortical zone is properly developed and populated by differentiating hemocytes as revealed by staining with the plasmatocyte marker, P1 (A, red). For clarity, magnified images of the LG areas are shown on the right side of the major panels, with the arrowheads demarcating the extent of the CZ. Upon activation of Wg signaling in prohemocytes by overexpression of Wg (B) or expression of the activated forms of D-β-catenin (Arm) (C, D), the development of the CZ is dramatically suppressed. In these mutants the CZ represents only one or two cell layer of P1-positive cells(arrowheads).