Table 1.
Substance name (abbreviation) | Metabolite name (abbreviation) | Actionsa |
---|---|---|
Di-(2-ethylhexl) phthalate (DEHP) | Mono-(2-ethylhexyl)-phthalate (MEHP) | Agonists of PPARα and PPARγ (MEHP, MnBuP, MBzP) [35]. |
Dibutyl phthalate (DBP) | Mono-butyl phthalate (MnBuP) | Leydig cell aggregation (DEHP, DBP) [30,31]. |
Benzyl butyl phthalate (BBP) | Mono-butyl Benzyl phthalate (MBzP) | Inhibition of T and INSL3 production (DEHP, DBP) [29–31,46–49]. |
Di-(isononyl) phthalate (DINP) | Mono-isononyl phthalate (MiNP) | |
Di-(isodecyl) phthalate (DIDP) | Mono-isodecyl phthalate (MiDP) | |
Di-n-octyl phthalate (DnOP) | Mono-n-octyl phthalate (MnOP) | |
Di-n-hexyl phthalate (DnHP) | Mono-n-hexyl phthalate (MnHP) | |
Diethyl phthalate (DEP) | Mono-ethyl phthalate (MEP) |
Actions pertain to all listed phthalates.