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. 2009 Jul 20;3:22. doi: 10.3389/neuro.11.022.2009

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Copyright © 2009 Dinov, Van Horn, Lozev, Magsipoc, Petrosyan, Liu, MacKenzie-Graham, Eggert, Parker and Toga.

This is an open-access article subject to an exclusive license agreement between the authors and the Frontiers Research Foundation, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are credited.

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Comparison of the four volume and shape measures for both times (baseline and 12-month follow up) across the three cohorts for one region of interest – the Right Superior Frontal Gyrus. T1 and T1 labels represent baseline and follow-up time scans. The statistics signature vector includes MeanCurv, average global shape mean curvature; MeanSurf, total shape surface area; MeanFract, mean global shape fractal dimension; and MeanVol, volume of the inside region of the shape. The three different cohorts, NC, MCI and AD, are colored in blue, green and red, respectively.