Figure 3.
Quantile-Quantile plots. Survival time quantiles calculated from control cohort survival times are plotted against corresponding survival time quantiles calculated from experimental cohort survival times. Part (A) shows a QQ plot for the Pit1(dw/dw) comparison and part (B) shows a QQ plot for the Clk1(+/−)(S2) comparison. The solid line represents a least-square regression line. Part (A) indicates that the AFT model appropriately describes the treatment effect for the Pit1(dw/dw) comparison, since points approximate a straight line. Part (B) suggests that the AFT model may not be appropriate for the Clk1(+/−)(S2) comparison, since points do not approximate a straight line. QQ plots for all 22 Table 1 comparisons are shown in Supplemental Data File 1.