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. 2009 Aug 14;5(8):e1000600. doi: 10.1371/journal.pgen.1000600

Figure 3. Alternative splicing changes in SCA8 and CUGBP1 RNA targets.

Figure 3

(A) RT-PCR of human autopsy tissue showing alternative splicing changes previously reported for DM1, NMDAR1 (exon 5) and MBNL1 (exon 7) also occur in SCA8. B) Diagram summarizing relative position of CUG-BP1 CLIP tags in genes. Boxes = exons (open = UTR; black-ORF); thick grey line = intergenic regions. Also indicated are tags that overlap intron/exon, orf/3′ UTR and 3′ UTR/intergenic junctions with the number of unique tags for each location in parentheses.