FIGURE 2.

Changes of protein detected by RPPA. a, heat map of protein levels detected by RPPA. The biomarkers, a protein or a phosphorylated isotype detected with specific antibodies, are arrayed on the horizontal axis, and the control and NSC-741909-treated samples are arrayed on the vertical axis. The levels of each biomarker are presented with colors, with red for highest and green for lowest. b, the time-dependent changes of phosphorylated P38 (p-P38), JNK (p-JNK), and ERK (p-ERK). The values represent signal intensity detected at each time point as indicated. C, control sample; T, NSC-741909-treated sample.