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Cation selectivity of hCNT3 and mutants. Mediated uptake of 20 μm radiolabeled uridine in transport medium containing 100 mm NaCl, pH 7.5 (black bars), ChCl, pH 5.5 (open bars), or ChCl, pH 7.5 (hatched bars), for oocytes producing hCNT3 mutants (as indicated) or wild-type hCNT3 is shown. Values were corrected for basal nonmediated uptake in control water-injected oocytes and are means ± S.E. of 10–12 oocytes.
