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Lineweaver-Burk plots of DMGO-catalyzed dimethylglycine oxidation inhibition by an analogue of the lactone intermediate and folinic acid. 1-Methyl-3-pyrrolidinol (A) and folinic acid (B) were used as inhibitors of DMGO oxidase activity. Results are means ± S.D. calculated from three independent experiments using the indicated inhibitor concentrations. The Ki for 1-methyl-3-pyrrolidinol was determined as 4 ± 0.2 mm.
