Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Percentage inhibition of 0.5 μm [3H]MTX influx by 1 μm folic acid
Influx was assessed at pH 5.5 and 37 °C over 1 min. Data are the mean ± S.E. from three independent experiments.
| Inhibition | |
|---|---|
| % | |
| WT-PCFT | 33.0 ± 2.2 |
| H247A | 76.4 ± 5.2 |
| H247R | 77.8 ± 4.3 |
| H247Q | 73.4 ± 5.1 |
| H247E | 75.3 ± 3.8 |
