Table 3. Quantitative trait genome wide association top significant results.
Chromosome | Gene Context | SNP | Coordinate(Build 36.3) | Location | Genomic context - Distance to gene | p-value | Supporting Information |
1 | AL157404.18 - S100A5 | rs4845552 | 151746622 | INTERGENIC | 7 Kbp from AL157404.18 | 6.23×10−6 | Figure S1 - Table S1 |
5 | AC026790.5 | rs682748 | 17201911 | INTERGENIC | 9 Kbp from the upstram of AC026790.5 | 8.14×10−6 | Figure S2 - Table S2 |
5 | AC022418.5 | rs7727656 | 25796436 | INTERGENIC | desert region | 8.27×10−6 | Figure S3 - Table S3 |
5 | AC104108.3 -SCAMP1 - LHFPL2 | rs6881634 | 77666610 | INTERGENIC | 14 Kbp from AC104108.3 | 1.93×10−6 | - Table S4 |
5 | ARSB | rs337847 | 78295644 | INTRONIC | intron 3 | 6.71×10−6 | Figure S5 - Table S5 |
5 | EFNA5 | rs10074258 | 107010459 | INTRONIC | intron1 | 2.15×10−7 | Figure S6 - Table S6 |
5 | EFNA5 | rs12654281 | 107068341 | INTERGENIC | 30 Kbp from 5′UTR of EFNA5 | 3.72×10−7 | Figure S6 - Table S6 |
5 | EFNA 5 | rs12657273 | 107074597 | INTERGENIC | 36 Kbp from 5′UTR of EFNA5 | 8.92×10−6 | Figure S6 - Table S6 |
7 | AC096553.4 | rs9918508 | 9505804 | INTERGENIC | desert region | 8.49×10−6 | Figure S7 - Table S7 |
7 | IKZF1 - AC020743.7 | rs2124799 | 50240560 | INTERGENIC | desert region - 75 Kbp from IKFZ1 | 8.54×10−6 | Figure S8 - Table S8 |
7 | IKZF1 - AC020743.7 | rs10276619 | 50283898 | INTERGENIC | desert region - 31 Kbp from IKFZ1 | 2.94×10−6 | Figure S8 - Table S8 |
7 | MAGI2 | rs11525066 | 78013913 | INTRONIC | intron 3 | 2.85×10−6 | Figure S9 - Table S9 |
8 | MAL2 | rs1364705 | 120293987 | INTRONIC | intron 2 | 8.92×10−6 | Figure S10 - Table S10 |
9 | PRUNE2 | rs10781380 | 78597964 | INTRONIC | intron 6 | 7.13×10−7 | Figure S11 - Table S11 |
9 | RP11-232A1.1 | rs10867752 | 83204857 | INTERGENIC | 8 Kbp from the upstream of RP11-232A1.1 | 3.08×10−6 | Figure S12 - Table S12 |
11 | ETS1 | rs6590322 | 127711620 | INTERGENIC | desert region | 9.37×10−6 | Figure S13 - Table S13 |
12 | ARID2 - SFRS2IP | rs1373549 | 44772105 | INTERGENIC | 100 Kbp downstream SFRS2IP | 7.80×10−6 | Figure S14 - Table S14 |
12 | CAND1 | rs1082714 | 65915098 | INTERGENIC | 34 Kbp from 5′UTR of CAND1 | 4.93×10−6 | Figure S15 - Table S15 |
13 | RP11-506F17.1 | rs9301535 | 85984283 | INTERGENIC | desert region | 7.90×10−6 | Figure S16 - Table S16 |
13 | RP11-506F17.1 | rs4773460 | 86040858 | INTERGENIC | desert region | 1.93×10−6 | Figure S16 - Table S16 |
14 | FRMD6 - AL079307.7 | rs11626056 | 51303026 | UPSTREAM | upstream region of AL079307.7 | 1.18×10−6 | Figure S17 - Table S17 |
20 | C20orf132 | rs8115854 | 35199751 | NON_SYNONYMOUS_CODING | exon 11 - non-synonymous coding | 2.09×10−6 | Figure S18 - Table S18 |
20 | RPN2 | rs6031882 | 35243197 | INTRONIC | intron 1 | 6.20×10−6 | Figure S18 - Table S18 |
20 | ZBP1 | rs2073145 | 55624040 | NON_SYNONYMOUS_CODING;SPLICE_SITE | exon 2 - non-synonymous coding; splice site | 2.13×10−6 | Figure S19 - Table S19 |
21 | FDPSP | rs1888414 | 20699601 | INTERGENIC | desert region - 16 Kbp from FDPSP | 2.41×10−7 | Figure S20 - Table S20 |
Quantitative trait analysis for the interaction between hippocampal grey matter volume (either left or right hemisphere) and SNPs from the genome-wide association study. All listed genes have at least one SNP in the left or right hippocampi at≤10−6. The chromosome number, gene context, SNP name (rs number), SNP base-pair position (build 36.3), physical location or SNP function (consequence type) are presented ordered by p-value.