Table 3.

Outcomes reported (X) in randomized clinical trials of perioperative N-acetylcysteine after cardiac surgery

Author	Acute kidney injury	Maximum change in creatinine	Peak post-operative creatinine	Long-term kidney function	Haemodialysis	Deatha	Length of stay (ICU)	Length of stay (hospital)
Adabag et al.23	Xb	Xb	Xb	Xc	X	X	X	X
Barr, 200824	Xd			Xe	X	X	X	X
Burns, 200525	Xb				X	X	X	X
El-Hamamsy et al.26	Xb	Xb	Xb		X	X	X	X
Fischer et al.27		Xb	Xb		X	X
Haase et al.28	Xb	Xb	Xb		X	X	X	X
Orhan et al.29	Xb	Xb	Xb		X	X	X	X
Ristikankare et al.30	Xb	Xb	Xb		X	X	X
Sisillo et al.31	Xd	Xd	Xd		X	X	X
Wijeysundera et al.32	Xd	Xd	Xd		X	X	X	X

ICU, intensive care unit.

^aIn-hospital or 30-day.

^bBy post-operative Day #5.

^cPost-operative Day #30.

^dBy post-operative Day #3.

^ePost-operative Day #14.