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. Author manuscript; available in PMC: 2009 Aug 1.
Published in final edited form as: Genet Epidemiol. 2009 Feb;33(2):151–163. doi: 10.1002/gepi.20368

TABLE II.

Means and standard deviations of parameter estimates: with number of cases = 200, 500 and, 800, 1,000

# Cases ea ec eâ eĉ P^D P^(Dhap5) r^
(a) 200 (Method L1) 1 1 1.29 (0.23) 1.02 (0.55) 0.44 (0.04) 0.94 (0.23) 0.66 (0.06)
1.2 1 1.39 (0.31) 0.91 (0.52) 0.45 (0.04) 0.90 (0.31) 0.67 (0.06)
1.5 1 1.62 (0.42) 1.05 (0.52) 0.44 (0.04) 0.94 (0.25) 0.72 (0.07)
2 1 2.22 (0.49) 1.22 (0.73) 0.42 (0.04) 0.95 (0.22) 0.80 (0.07)
1.5 1.5 1.90 (0.68) 1.72 (0.92) 0.44 (0.04) 0.75 (0.42) 0.71 (0.12)
2 1.5 2.57 (0.76) 1.83 (0.88) 0.44 (0.04) 0.84 (0.36) 0.77 (0.09)
200 (Method L2) 1 1 1.27 (0.21) 1.00 (0.43) 0.45 (0.04) 0.87 (0.34) 0.64 (0.05)
1.2 1 1.34 (0.27) 0.93 (0.32) 0.44 (0.05) 0.91 (0.29) 0.66 (0.06)
1.5 1 1.58 (0.36) 1.01 (0.35) 0.39 (0.06) 0.94 (0.23) 0.72 (0.09)
2 1 2.07 (0.36) 0.92 (0.25) 0.35 (0.07) 0.96 (0.20) 0.78 (0.12)
1.5 1.5 1.76 (0.60) 1.57 (0.78) 0.40 (0.08) 0.82 (0.37) 0.67 (0.14)
2 1.5 2.46 (1.04) 1.69 (0.96) 0.32 (0.16) 0.75 (0.42) 0.57 (0.28)
200 (Method L3) 1 1 1.28 (0.21) 0.98 (0.42) 0.45 (0.04) 0.87 (0.34) 0.64 (0.05)
1.2 1 1.35 (0.27) 0.91 (0.34) 0.44 (0.05) 0.90 (0.30) 0.66 (0.06)
1.5 1 1.59 (0.36) 1.06 (0.41) 0.39 (0.06) 0.95 (0.21) 0.73 (0.07)
2 1 2.18 (0.40) 0.99 (0.33) 0.35 (0.05) 0.98 (0.13) 0.81 (0.07)
1.5 1.5 1.85 (0.63) 1.78 (0.88) 0.39 (0.06) 0.89 (0.29) 0.71 (0.11)
2 1.5 2.52 (0.72) 1.95 (0.94) 0.35 (0.06) 0.98 (0.14) 0.79 (0.10)
500 (Method L1) 1 1 1.12 (0.11) 0.95 (0.29) 0.45 (0.02) 0.98 (0.13) 0.64 (0.03)
1.2 1 1.26 (0.17) 1.02 (0.34) 0.44 (0.03) 0.99 (0.08) 0.68 (0.04)
1.5 1 1.60 (0.23) 1.04 (0.28) 0.42 (0.04) 0.99 (0.08) 0.75 (0.06)
2 1 2.15 (0.27) 1.04 (0.31) 0.40 (0.03) 1.00 (0.00) 0.84 (0.05)
1.5 1.5 1.76 (0.36) 1.75 (0.67) 0.43 (0.04) 0.84 (0.36) 0.73 (0.10)
2 1.5 2.41 (0.54) 1.76 (0.68) 0.43 (0.04) 0.89 (0.31) 0.79 (0.09)
500 (Method L2) 1 1 1.12 (0.10) 0.96 (0.23) 0.46 (0.02) 0.98 (0.15) 0.64 (0.03)
1.2 1 1.25 (0.17) 0.99 (0.22) 0.43 (0.04) 0.99 (0.08) 0.67 (0.04)
1.5 1 1.57 (0.21) 1.02 (0.18) 0.37 (0.05) 1.00 (0.00) 0.76 (0.06)
2 1 2.08 (0.27) 0.94 (0.15) 0.32 (0.06) 0.98 (0.15) 0.82 (0.13)
1.5 1.5 1.75 (0.44) 1.77 (0.64) 0.40 (0.07) 0.88 (0.30) 0.68 (0.12)
2 1.5 2.33 (0.83) 1.50 (0.54) 0.30 (0.17) 0.74 (0.43) 0.55 (0.30)
500 (Method L3) 1 1 1.12 (0.10) 0.96 (0.24) 0.45 (0.02) 0.98 (0.13) 0.64 (0.03)
1.2 1 1.25 (0.18) 0.99 (0.24) 0.43 (0.04) 0.99 (0.08) 0.67 (0.04)
1.5 1 1.57 (0.21) 1.04 (0.20) 0.37 (0.05) 1.00 (0.00) 0.76 (0.06)
2 1 2.14 (0.25) 0.98 (0.19) 0.32 (0.03) 1.00 (0.00) 0.85 (0.05)
1.5 1.5 1.76 (0.35) 1.82 (0.72) 0.38 (0.05) 0.95 (0.20) 0.74 (0.09)
2 1.5 2.50 (0.58) 1.75 (0.81) 0.35 (0.05) 0.99 (0.11) 0.80 (0.09)
800 (Method L1) 1 1 1.11 (0.08) 0.94 (0.21) 0.45 (0.02) 0.99 (0.08) 0.64 (0.03)
1.2 1 1.23 (0.16) 1.04 (0.28) 0.44 (0.03) 0.99 (0.08) 0.68 (0.04)
1.5 1 1.59 (0.16) 1.02 (0.24) 0.40 (0.03) 1.00 (0.06) 0.77 (0.05)
2 1 2.10 (0.21) 1.04 (0.24) 0.39 (0.03) 1.00 (0.00) 0.86 (0.04)
1.5 1.5 1.67 (0.26) 1.72 (0.51) 0.42 (0.04) 0.91 (0.28) 0.75 (0.08)
2 1.5 2.32 (0.42) 1.68 (0.52) 0.42 (0.04) 0.92 (0.27) 0.81 (0.08)
800 (Method L2) 1 1 1.10 (0.07) 0.97 (0.15) 0.46 (0.02) 0.99 (0.08) 0.64 (0.02)
1.2 1 1.22 (0.15) 1.01 (0.17) 0.43 (0.03) 1.00 (0.00) 0.67 (0.04)
1.5 1 1.57 (0.14) 1.00 (0.15) 0.36 (0.04) 1.00 (0.00) 0.78 (0.05)
2 1 2.06 (0.19) 0.94 (0.12) 0.31 (0.03) 0.99 (0.09) 0.85 (0.08)
1.5 1.5 1.71 (0.30) 1.75 (0.49) 0.38 (0.07) 0.94 (0.22) 0.70 (0.12)
2 1.5 2.16 (0.71) 1.49 (0.50) 0.29 (0.16) 0.76 (0.42) 0.57 (0.31)
800 (Method L3) 1 1 1.10 (0.08) 0.96 (0.16) 0.46 (0.02) 0.99 (0.08) 0.64 (0.02)
1.2 1 1.22 (0.15) 1.01 (0.18) 0.43 (0.03) 1.00 (0.00) 0.67 (0.04)
1.5 1 1.57 (0.14) 1.01 (0.16) 0.36 (0.04) 1.00 (0.00) 0.78 (0.05)
2 1 2.09 (0.18) 0.98 (0.13) 0.31 (0.03) 1.00 (0.00) 0.87 (0.04)
1.5 1.5 1.67 (0.25) 1.74 (0.52) 0.36 (0.05) 0.99 (0.09) 0.77 (0.08)
2 1.5 2.39 (0.40) 1.64 (0.68) 0.34 (0.05) 1.00 (0.04) 0.82 (0.08)
1,000 (Method L1) 1 1 1.10 (0.07) 0.94 (0.19) 0.45 (0.01) 0.99 (0.11) 0.64 (0.02)
1.2 1 1.21 (0.14) 1.03 (0.27) 0.44 (0.03) 0.98 (0.13) 0.68 (0.04)
1.5 1 1.58 (0.14) 1.03 (0.22) 0.40 (0.03) 1.00 (0.00) 0.78 (0.05)
2 1 2.08 (0.18) 1.03 (0.21) 0.38 (0.02) 1.00 (0.00) 0.87 (0.04)
1.5 1.5 1.65 (0.22) 1.69 (0.41) 0.42 (0.04) 0.93 (0.24) 0.77 (0.07)
2 1.5 2.28 (0.35) 1.66 (0.42) 0.42 (0.04) 0.95 (0.23) 0.82 (0.08)
1,000 (Method L2) 1 1 1.08 (0.07) 0.97 (0.13) 0.46 (0.02) 1.00 (0.00) 0.63 (0.01)
1.2 1 1.21 (0.13) 1.01 (0.15) 0.43 (0.03) 0.99 (0.08) 0.67 (0.04)
1.5 1 1.57 (0.12) 1.00 (0.13) 0.35 (0.03) 1.00 (0.00) 0.79 (0.05)
2 1 2.07 (0.15) 0.93 (0.09) 0.31 (0.02) 1.00 (0.00) 0.86 (0.03)
1.5 1.5 1.66 (0.24) 1.66 (0.39) 0.37 (0.07) 0.96 (0.19) 0.71 (0.12)
2 1.5 2.17 (0.64) 1.44 (0.36) 0.29 (0.14) 0.81 (0.39) 0.61 (0.30)
1,000 (Method L3) 1 1 1.09 (0.07) 0.97 (0.14) 0.46 (0.02) 1.00 (0.00) 0.64 (0.01)
1.2 1 1.21 (0.13) 1.01 (0.16) 0.43 (0.03) 0.99 (0.08) 0.67 (0.04)
1.5 1 1.57 (0.13) 1.01 (0.13) 0.35 (0.03) 1.00 (0.00) 0.79 (0.05)
2 1 2.08 (0.18) 0.97 (0.13) 0.31 (0.02) 1.00 (0.00) 0.88 (0.03)
1.5 1.5 1.66 (0.24) 1.70 (0.48) 0.36 (0.05) 0.99 (0.08) 0.78 (0.08)
2 1.5 2.38 (0.37) 1.57 (0.61) 0.33 (0.04) 1.00 (0.01) 0.83 (0.08)