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. 2009 Apr 2;11(5):322–333. doi: 10.1007/s11307-009-0208-1

Fig. 6.

Fig. 6

Correlation of BPND from 2T1Mifvtm and 2T4ki, respectively, with Inline graphic for clinical [18F]FDDNP data obtained from several regions of interest and subjects. 2T4ki represents the reversible two-tissue plasma input model and 2T1Mifvtm the modified reversible two-tissue model, which includes an additional parallel single-tissue compartment for metabolites. For both models, BPND was estimated indirectly through calculation of distribution volume ratios.