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Representative MAP waveforms during steady-state 8-Hz pacing recorded from the left ventricular epicardia and endocardia of KCNE1−/− (a and c) and WT (b and d) hearts perfused with control solution (a and b) or 20 µM nicorandil (c and d). KCNE1−/− hearts had longer epicardial MAP waveforms (a) than WTs similarly perfused with control solution (b), and both were shortened by nicorandil (c and d) while endocardial MAPs were conserved in both (c and d)
