Table 2.
Manufacturer | Potential drawbacks | Potential benefits | |
---|---|---|---|
Lactate-buffered glucose containing Dianeal® | Baxter | Low pH | Ease of manufacture; low cost |
High GDP content | |||
Poor peritoneal membrane biocompatibility | |||
Infusion pain | |||
Local and systemic glucose exposure | |||
Icodextrin-containing; lactate buffered | Baxter | Hypersensitivity | Sustained ultrafiltration |
Low pH | Preservation of RRF | ||
Licensed for single daily use only | Hypertonic glucose replacement | ||
Lactate containing | Reduced hyperglycemia | ||
Improved short-term systemic hemodynamic profile | |||
Desirable effects on metabolic profile and body composition | |||
Amino-acid containing; Nutrineal® | Baxter | Low pH | No GDPs |
Licensed for single daily use only (avoid exacerbation of uremic symptoms and acidosis) | Avoid systemic and peritoneal glucose exposure | ||
Peritoneal membrane protection | |||
Enhance nutrition |
GDP glucose degradation product, RRF residual renal function