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IL-8 EC silencing induces VCAM-1 during atheroprone flow. EC-siIL8 was optimized via RT-PCR (A) and ELISA (B). SMCs/ECs were examined for mRNA changes after atheroprone flow for EC-siIL8 or EC-CP (C). (Mean±SE; n=3; *P≤0.05 to untreated; #P<0.05 to IL-1β–treated; P<0.05 to IL-1β–treated CP; CP indicates control pool; RP, replated).
