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. Author manuscript; available in PMC: 2009 Aug 3.
Published in final edited form as: Nature. 2008 Jan 16;451(7179):730–733. doi: 10.1038/nature06498

Figure 1. Pgc expression in pole cells is essential for the repression of CTD Ser 2 phosphorylation.

Figure 1

a, Pgc sequences of 12 Drosophila species. Conserved amino acid residues are highlighted by green shading. Note that no apparent Pgc orthologues can be found in other animal groups. b, Pgc expression in pole cells is complementary to pSer 2. Panels show the posterior pole of wild-type embryos immunostained for Pgc (green) and pSer 2 (magenta). Nuclei were counter-stained with 4,6-diamidino-2-phenylindole (DAPI; cyan). Pgc is concentrated in the nucleus (inset). c, Posterior poles of stage-4 embryos immunostained for pSer 2 (magenta) and Pgc (green). Nuclei were counter-stained with DAPI. Maternal genotypes are indicated. Note that pgc ORFfs RNA accumulates normally in the germ plasm (Supplementary Fig. 2).