Table 1.
Distribution of GI risk factors and recent/concomitant therapies across levels of the exposure.
| Variable | Coxib Users | NSAID Users | Prevalence Difference and 95% CI |
|---|---|---|---|
| U* | E[U*|X = 1] | E[U*|X = 0] | E[U*|X = 1] – E[U*|X = 0] |
| Patient Characteristics | |||
| Female Gender | 85.89% | 81.11% | 4.79% (4.09% – 5.48%) |
| Age ≥ 75 | 75.08% | 65.28% | 9.80% (8.95% – 10.64%) |
| History of GI Bleed | 1.71% | 1.11% | 0.60% (0.39% – 0.81%) |
| History of Peptic Ulcer Disease | 3.71% | 2.41% | 1.29% (0.99% – 1.60%) |
| History of Coronary Hospitalization or Procedure | 16.42 | 14.76 | 1.67% (1.00% – 2.33%) |
| Recent/Concomitant Rxs | |||
| Concomitant Use of GI-protective Drugs | 5.08% | 4.00% | 1.08% (0.71% – 1.46%) |
| Recent Use of GI-protective Drugs | 27.34% | 20.41% | 6.93% (6.16% – 7.70%) |
| Recent Use of Glucocorticoids | 8.73% | 7.80% | 0.94% (0.44% – 1.44%) |
| Recent Use of Warfarin | 13.25% | 6.53% | 6.71% (6.19% – 7.23%) |