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. 2009 Jul 6;119(8):2281–2290. doi: 10.1172/JCI38879

Figure 10. Improved outcome after blocking Nkg2d.

Figure 10

(A) Development of symptoms, weight gain, and survival after daily i.p. injections of 100 μg of anti-Nkg2d neutralizing antibodies (or IgG isotype control) into neonatal mice injected with saline or RRV on the first day of life. Saline, Nkg2d Ab: n = 8; RRV, Nkg2d Ab: n = 38; RRV, control IgG: n = 13. *P < 0.01. (B) H&E staining of representative longitudinal sections of murine extrahepatic bile ducts at different time points after injection of RRV on the first day of life, followed by the daily administration of 100 μg of blocking anti-Nkg2d antibodies. Scale bars: 50 μm.