Figure 5. Lysis of cholangiocytes by hepatic NK cells.

Mean (±SD) percentage of ⁵¹Cr release by the murine cholangiocyte line mCL after 5 hours of coculture with hepatic NK cells purified 7 days after saline injection or RRV inoculation into 1-day-old mice. The horizontal axis shows mCL (target) to NK (effector) cell ratios. n = 3 wells per group; results are representative of 2 independent experiments, with hepatic NK cells obtained from pools of 10–15 livers (*P < 0.01); arrows indicate nondetectable cells.