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. 2009 Jul 1;119(8):2423–2434. doi: 10.1172/JCI36908

Figure 4. Contribution of MR and GR to the aldosterone-mediated regulation of Per1.

Figure 4

Mouse IMCD-3 cells were transfected with a non-target control siRNA or siRNA for MR (MR10) or GR (GR10). Twenty-four hours later, cells were treated with vehicle or aldosterone for 1 hour. Changes in gene expression were measured using QPCR. Data are presented as mean ± SEM; n = 3. *P < 0.05 versus non-target siRNA–transfected cells treated with vehicle; †P < 0.05 versus non-target siRNA–transfected cells treated with aldosterone; NS, not significant versus non-target siRNA–transfected cells treated with vehicle.