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. Author manuscript; available in PMC: 2009 Aug 3.
Published in final edited form as: Bioorg Med Chem. 2008 Apr 25;16(11):6116–6123. doi: 10.1016/j.bmc.2008.04.050

Table 3.

A comparison of competition binding for selected 5-HT2A ligands using [3H]ketanserin and [3H]INBMeO. Ki values given are nM ± SEM.

Displacing
Liganda 		A20 Cells Hh2A cells
[3H]ketb [3H]INBc [3H]ketb [3H]INBc
5-HT 120 ± 21 160 ± 17 130 ± 65 150 ± 20
Cinanserin 17 ± 2.8 24 ± 2.4 13 ± 5.1 22 ± 5.9
DOI 29 ± 5.2 28 ± 8 13 ± 2.0 14 ± 1.2
LSD 2.6 ± 0.9 4.0 ± 0.5 3.1 ± 0.7 3.5 ± 0.4
a

(n = 3)

b

[3H]ketanserin

c

[3H]INBMeO