Figure 4. Reponse to paired pulse stimuli in Q54 hippocampal slices.
Q54 mice (n = 5) do not show a significant difference in comparison to WT mice (n = 5), however both groups maintain facilitation despite a short paired pulse delay suggesting compromised local inhibitory network activity. Characteristic extracellular trace of paired pulse stimulus is shown in inset (scale is 1 mV, 40 ms; ▼ indicates stimulus artifact; error bars represent SEM).