Table 1. Selected Baseline Participant Characteristics by PTH Tertiles in Older Diabetic Adults*.
| Median PTH, pg/mL (interquartile range) | 1st Tertile | 2nd Tertile | 3nd Tertile | P-value |
|---|---|---|---|---|
| 31.0 (26.7-36.4) | 48.1 (44.2-52.4) | 72.8 (65.0-95.2) | ||
| Age (yrs) | 73.3 ± 2.8 | 73.5 ± 2.9 | 74.0 ± 2.8 | 0.10 |
| Female (%) | 36.3 | 41.1 | 49.0 | 0.07 |
| Black race (%) | 40.1 | 55.7 | 68.2 | <0.001 |
| Pittsburgh field center (%) | 51.0 | 51.9 | 46.5 | 0.59 |
| < High school education (%) | 35.0 | 35.4 | 35.0 | 0.99 |
| Current smoker (%) | 10.8 | 8.2 | 10.2 | 0.72 |
| Current drinker (%) | 35.7 | 45.6 | 26.1 | 0.002 |
| <500 kcal/wk walking or exercise (%) | 56.0 | 55.7 | 67.5 | 0.05 |
| BMI (kg/m2) | 28.5 ± 4.6 | 29.2 ± 4.6 | 30.5 ± 5.0 | <0.001 |
| Winter/spring season (%) | 49.7 | 55.1 | 67.5 | 0.005 |
| Poor eyesight (%) | 3.2 | 5.7 | 7.6 | 0.22 |
| Cognition (3MS score) | 88.6 ± 10.2 | 88.2 ± 8.6 | 87.4 ± 8.6 | 0.49 |
| Depressive symptoms (CES-D score) | 5.3 ± 6.5 | 4.6 ± 5.2 | 4.5 ± 5.7 | 0.40 |
| Fell in the previous 12 months (%) | 17.8 | 26.6 | 19.8 | 0.14 |
| Chronic conditions | ||||
| Cardiovascular disease (%) | 23.6 | 33.5 | 35.7 | 0.05 |
| Osteoporosis (%) | 7.0 | 6.3 | 8.3 | 0.79 |
| Knee pain (%) | 14.0 | 15.8 | 19.8 | 0.38 |
| Urinary incontinence (%) | 15.9 | 19.0 | 17.8 | 0.77 |
| Medications | ||||
| Anti-hypertensive agents (%) | 63.1 | 66.5 | 73.2 | 0.14 |
| Hypotensive agents (%) | 7.6 | 5.7 | 8.9 | 0.55 |
| Insulin (%) | 16.6 | 17.1 | 32.5 | <0.001 |
| Oral hypoglycemics (%) | 55.4 | 49.4 | 47.1 | 0.32 |
| Benzodiazepines (%) | 6.4 | 2.5 | 1.9 | 0.07 |
| SSRIs (%) | 2.6 | 0.6 | 1.3 | 0.36 |
| Total # of medications | 4.2 ± 2.5 | 4.1 ± 3.2 | 4.8 ± 2.9 | 0.08 |
| Multivitamin use (%) | 30.1 | 30.3 | 20.6 | 0.09 |
| Calcium supplement use (%) | 13.4 | 7.6 | 7.0 | 0.10 |
| Vitamin D supplement use (%) | 8.3 | 3.2 | 0.6 | 0.002 |
| Cystatin C (mg/dL) | 1.05 ± 0.31 | 1.03 ± 0.21 | 1.18 ± 0.38 | <0.001 |
| Hemoglobin A1c | 7.98 ± 1.33 | 8.02 ± 1.56 | 8.16 ± 1.65 | 0.54 |
| Health ABC SPPB summary score | 2.08 ± 0.58 | 2.01 ± 0.59 | 1.91 ± 0.61 | 0.04 |
*
Means ± SD or frequencies with chi-square or ANOVA to evaluate the distribution. PTH: parathyroid hormone; BMI: body mass index; 3MS: Modified Mini-Mental State Examination; CES-D: Center for Epidemiologic Studies Depression Scale; SSRI: selective serotonin reuptake inhibitors; SPPB: Short Physical Performance Battery.