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. 2008 Oct 17;40(4):433–442. doi: 10.1165/rcmb.2007-0392OC

Figure 5.

Figure 5.

Measurements of serum OVA-specific IgE and IgG1 levels in bone marrow chimeric mice after OVA sensitization and challenge, and of the Th2 cytokines IL-5 and -13 from peribronchial lymph nodes harvested from these mice. (A) Levels of serum OVA-specific IgE and IgG1 in lethally irradiated BL6 or CD38−/− mice, reconstituted either with parental or with reciprocal bone marrow, after OVA sensitization and challenge (S/C). (B) Levels of IL-5 and IL-13 in supernatants from peribronchial lymph node cultured for 4 days in the presence of 100 μg/ml OVA that were obtained from lethally irradiated BL6 or CD38−/− mice, reconstituted either with parental or with reciprocal bone marrow, after OVA sensitization and challenge (S/C). *P < 0.05 for BL6 S/C compared with CD38−/− > BL6 S/C. #P < 0.05 for CD38−/− S/C compared with BL6 > CD38−/− S/C.