TABLE 5.
Effects on LINE-1 Methylation
|
||
---|---|---|
Coeff* (95% CI) | P Value | |
Black carbon (4-h + 7-d model) | ||
4-h mean | −0.05 (−0.11 to 0.02) | 0.16 |
7-d mean | −0.09 (−0.16 to −0.02) | 0.008 |
PM2.5 (4-h + 7-d model) | ||
4-h mean | −0.04 (−0.11 to 0.03) | 0.24 |
7-d mean | −0.11 (−0.18 to −0.05) | 0.001 |
For definition of abbreviations, see Table 4.
Standardized correlation coefficients, expressing the fraction of a standard deviation change in DNA methylation associated with a standard deviation change in pollutant level, adjusted for age, body mass index, cigarette smoking (never, former, current), pack-years, statin use, fasting blood glucose, diabetes mellitus, percent lymphocytes and neutrophils in differential blood count, day of the week, season, and outdoor temperature.