Figure 4.

The positions of PAM and Asp (elemental color) in the active site of R_{236_PA} structure compared to (a) the positions of PAM and malonate (thin, black) in the R_PM structure and (b) the positions of PALA in the R_PALA structure (thin, black, only the residues that are in different positions are shown). The two structures were first superimposed using SEQUOIA.⁴¹ The comparison of one catalytic chain (grey, red) of ATCase along with the 80's loop of the adjacent catalytic chain (yellow, 80's loop*) of the R_{236_PA} structure (c) with the T_CP structure, and (d) with the R_{236_P} structure. The width of the tube is proportional to the RMS deviation between the α-carbon positions of the two structures. PAM and Asp are shown to indicate the active site position.