Skip to main content
. Author manuscript; available in PMC: 2009 Aug 3.
Published in final edited form as: J Mol Biol. 2007 Jun 9;371(5):1261–1273. doi: 10.1016/j.jmb.2007.06.011

Figure 5.

Figure 5

(a) The proposed conformation of the tetrahedral intermediate of the reaction between CP and Asp as catalyzed by ATCase.26 The postulated proton transfer between a terminal phosphate oxygen and the amino group of Asp is indicated by the long dashed line. (b) The active site of the R236_PA structure showing the position of the cyclic model of the tetrahedral intermediate (Int, thin, black) determined using AUTODOCK.27 For comparison, PAM from the R236_PA structure is also shown. The hydrogen that is part of the six-membered ring of the tetrahedral intermediate is shown.