TABLE 1.
PATIENT CHARACTERISTICS
| Current-smokers | Former-smokers | Nonsmokers/Long-term Quitters | P value* | |
|---|---|---|---|---|
| Patients, n (%) | 30 (40) | 22 (29) | 23 (31) | |
| Age, mean (SD) | 63 (9) | 64 (9) | 68 (12) | 0.131 |
| Sex, n (%) | 0.735 | |||
| Female | 15 (50) | 11 (50) | 14 (61) | |
| Male | 15 (50) | 11 (50) | 9 (39) | |
| PKY, mean (SD) | 60 (50) | 51 (34) | 4 (13) | <0.001 |
| Histology, n (%) | 0.013 | |||
| Adenocarcinoma | 19 (63) | 7 (32) | 17 (74) | |
| Squamous | 11 (37) | 15 (68) | 6 (26) | |
| Stage, n (%) | 0.259 | |||
| I | 16 (53) | 10 (45) | 12 (52) | |
| II | 7 (23) | 9 (41) | 3 (13) | |
| III | 6 (20) | 3 (14) | 8 (35) | |
| IV | 1 (3) | — | — | |
| Ethnicity, n (%) | 0.595 | |||
| Caucasian | 27 (90) | 21 (95) | 20 (87) | |
| Hispanic | — | — | 1 (4) | |
| African | 3 (10) | 1 (5) | 1 (4) | |
| Korean | — | — | 1 (4) | |
| DRC, mean (SD) | 8.23 (2.87) | 8.09 (2.32) | 8.06 (2.41) | 0.99 |
| BIC strand breaks, mean (SD) | 0.77 (0.37) | 0.64 (0.27) | 0.61 (0.27) | 0.352 |
Definition of abbreviations: BIC = bleomycin induced chromatin; DRC = DNA repair capacity; PKY = pack years.
*
Kruskal-Wallis test for groups with continuous outcomes; Fisher's exact test for categorical outcomes.