Table 4. The 10 most significant cancer-associated SELDI peaks in the serum analysis.
Peak | P-value (Wilcoxon's test) | Ratio (C/N) | ROC area |
---|---|---|---|
CM10 mz 6679 | 3.50 × 10−8 | 0.704 | 0.873 |
CM10 mz 4303# | 3.92 × 10−8 | 5.759 | 0.872 |
IMAC mz 9632 | 2.41 × 10−7 | 0.682 | 0.849 |
IMAC mz 3030# | 3.69 × 10−7 | 6.139 | 0.844 |
IMAC mz 133000 | 1.04 × 10−6 | 0.614 | 0.830 |
IMAC mz 3291# | 1.34 × 10−6 | 8.355 | 0.827 |
IMAC mz 4299# | 2.31 × 10−6 | 7.655 | 0.819 |
IMAC mz 6629 | 2.43 × 10−6 | 0.685 | 0.819 |
IMAC mz 3956 | 2.43 × 10−6 | 4.266 | 0.819 |
IMAC mz 9705 | 2.68 × 10−6 | 0.698 | 0.817 |
We present P-value for cancer vs non-cancer (Wilcoxon's test), cancer median peak height divided by non-cancer median peak height and area under the ROC curve. All of these peaks were also significant by LM and were not significantly associated with age, gender or H. pylori (P>0.05). Peaks arising from fragments of ITIH4 are marked with #.