Table 2. Univariate and multivariate analysis of metastasis-free and cancer-specific survival rate.

	Metastasis free (%)
	5 years	10 years	Log-rank test	Likelihood Ratio Chi-square	Cox
TNM stage
1	89.6	81.7	0.0003	3.2923	0.1928
2	75.0	42.9
3	52.5	46.7
Nuclear grade
1	88.5	82.9	0.0001	3.9556	0.1384
2	79.5	68.0
3 or 4	43.3	34.7
Microscopic venous invasion
Negative	81.8	73.1	NS
Positive	74.1	60.2
Annexin II expression
Negative	90.1	83.6	<0.0001	5.3228	0.021
Positive	63.0	46.5
	Cancer-specific survival (%)
	5 years	10 years	Log-rank test	Likelihood Ratio Chi-square	Cox
TNM stage
1	94.4	90.4	<0.0001	26.7984	<0.0001
2	91.8	73.3
3	74.1	63.6
4	25.2	0.0
Nuclear grade
1	97.6	97.6	<0.0001	17.0858	0.0002
2	81.3	69.0
3 or 4	42.0	33.7
Microscopic venous invasion
Negative	83.4	77.6	0.0011	0.0748	0.7845
Positive	63.4	53.9
Annexin II expression
Negative	84.2	81.9	0.0025	0.1022	0.7492
Positive	66.5	54.8