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The effects of Aβ1–40 on transcription factor activation in HBEC. Primary HBEC cultures were treated with 5 µM Aβ1–40, 5 µM scrambled Aβ peptides or 2 mM NaOH (vehicle) for 8 h. The levels of five transcription factors AP-1, CREB, GATA, GRE, and NFATc were increased over two-fold in Aβ-treated HBEC as compared to controls and scrambled Aβ-treated cells
