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. Author manuscript; available in PMC: 2010 Jul 22.
Published in final edited form as: J Am Chem Soc. 2009 Jul 22;131(28):9695–9703. doi: 10.1021/ja9006707

Figure 3. Mulitplexed nucleic acid cell sorting of antigen-specific T cells.

Figure 3

(A) Tyrosinase p/MHC tetramer conjugated to ssDNA sequence A’ was hybridized to an array printed with DNA complement strand A and non-complement strands B and C (dashed circles). Jurkat α −Tyr cells were localized to spot A only. (B) A 1:1:1 mixture of Jurkatα-a-MART-1 (red), Jurkatα -Tyr (green) and Jurkatα–NY-ESO-1 cells was selectively sorted on an array hybridized with MART-1, tyrosinase, and NY-ESO-1 p/MHC ssDNA-tetramers (top left). The remaining three panels are representative images of spots A, B and C.