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. 2009 Aug 12;4(8):e6616. doi: 10.1371/journal.pone.0006616

Figure 3. Histological Analysis of Rpe65−/−/Bax−/− Retinas at 2 Months of Age.

Figure 3

(A) Examination of retinal morphology (600×) and (B) Counting rows of rod nuclei within the ONL of Bax-deficient retinas showed no increase in outer nuclear layer thickness as compared with wt retinas. A slight decrease in ONL thickness was only shown in Rpe65−/− retinas. * p<0.001 by ANOVA test for Rpe65−/− versus wt, Bax−/− and Rpe65−/−/Bax−/−. (C) Early shortening of OS length at the onset of retinal degeneration in Rpe65−/− mice was not observed in Rpe65−/−/Bax−/− mice. ONL, outer nuclear layer; INL, inner nuclear layer; OS, outer segment.