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. Author manuscript; available in PMC: 2009 Aug 4.
Published in final edited form as: J Neurochem. 2009 Feb 13;109(3):733–743. doi: 10.1111/j.1471-4159.2009.05990.x

Fig. 3. Hypoglycemia increases the enhancement of nuclear and cytoplasmic P-Smad levels produced by both BMP7 alone and a BMP7 + BDNF combination.

Fig. 3

Cultures grown for 5 days in vitro were subjected to hypoglycemic stress (B, D) or to serum-free medium with normal glucose (A, C). During the last hour, BMP7 alone, BDNF alone, or BMP7 + BDNF were added, and nuclear (A, B) and cytoplasmic (C, D) P-Smad fluorescence were measured, as in Fig. 1. * indicates significant increase from control or indicated group with p<0.01, using one-way ANOVA followed by Newman-Keuls test; each group represents measurements of P-Smad fluorescence in at least 25 cells.