Table 1. Regional percent difference in resting [¹⁸F]FDG uptake (left vs. right) at 28 and 58 days after surgical implant into the right striatum.

Regions of interest (ROIs) were used to calculate hemisphere differences for controls (anesthesia only) or surgically implanted animals.

	Controls		Surgical Implants†
Region	Scan 1 (n=7) % Δ (SEM)	Scan 2 (n=7) % Δ (SEM)	Scan 1 (n=7) % Δ (SEM)	Scan 2 (n=6) % Δ (SEM)
Frontal Cortex	2.04 (1.78)	3.47 (1.02)	-11.30 (1.58)***	-13.71 (2.69)***
Motor Cortex (M1)	1.05 (0.92)	-0.62 (1.19)	-24.65 (4.83)***	-25.64 (3.29)***
Sensory Cortex (S1)	-5.20 (0.50)	-5.26 (0.82)	-12.96 (2.59)	-17.04 (3.15)**
Auditory Cortex	0.58 (2.03)	-1.31 (0.92)	-8.48 (2.95)*	-9.25 (3.23)
Visual Cortex (V1-V2)	8.18 (2.12)	4.78 (1.27)	-5.63 (3.52)***	-10.71 (2.78)***
Caudate/Putamen	-3.94 (1.34)	-1.92 (1.34)	-8.85 (2.89)	-15.81 (2.50)***
Thalamus	2.40 (1.84)	-0.13 (0.94)	-7.40 (2.44)*	-9.98 (1.68)*
Hippocampus	-3.53 (3.22)	-3.13 (0.81)	-5.12 (0.67)	-2.35 (2.31)
Colliculi (Superior)	-3.79 (1.86)	-3.57 (1.40)	-0.22 (5.42)	-3.66 (2.60)
Cerebellum	2.73 (1.24)	-3.43 (2.52)	-7.11 (5.38)	-0.26 (1.96)

^†Comparisons were made between groups using a two-way ANOVA (region x group) followed by post-hoc Bonferroni analysis

^*different from scan-specific control group, p < 0.05;

^**different from scan-specific control group, p < 0.01;

^***different from scan-specific control group, p < 0.001